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The solid was washed (DCM, EtOAc) then purified by Biotage C-18 reverse phase flash chromatography (30%- 100% MeOH vs 0.1%) aqueous formic acid) to give the title compound Base Structure-C-PIPM (227.6 mg, 30%) after treatment with HCl and lyophilization

van der Vijgh, W

PMID: 32457419 31

It is helping them build a routine, understand the value of cellular health, and feel confident in their long-term wellness journey

Generally, cytoskeletal motor proteins are ATPases that use the energy released from ATP hydrolysis to move along the cytoskeletal elements of MTs and F-actin (Lee and Liu, 2004)

In contrast, the genetic aetiology of a specific syndrome can be due to mutations in different genes, as in the case of Leigh syndrome (LS), which can be caused by nDNA and mtDNA mutations in more than 100 genes overall [12]